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Home » Chemistry Homework Help » Biochemistry » Pancreatic Juice
Pancreatic Juice
This is also a clear watery secretion. It contains 1.5% solids and 98.5% water. It has a pH of 7.0 to 8.0 about 500 – 800 ml are secreted per day. Two thirds of the solids are organic and consist main of the enzymes trypsinogen and chymotrypsinogen which are zymogene (inactive) from of the proteolytic enzymes trypsin and Chymotrypsin. An enzyme produced by the intestines called enterokinase acts of these inactive enzymes and converse them to the active zymase forms. The activation involves hydrolytic removal of a small peptide form the inactive enzymes. Once active trypsin is produced thus in small amounts it can activate the rest of trypsinogen and chymotrypsinogen (autocatalysis). Another proteolytic enzyme called Carboxypeptidase (secreted probably as a procarboxypeptidase and activated by trypsin) is also present. A biolytic there is also a potent pancreatic amylase. Decides these principal enzymes there are also other enzymes cholesterol esterase, ribounclease deoxyribonculesase collagenases and phospholipases.

One third of the scolds (0.5%) is inorganic and consists mainly of the chloride and bicarbonate of sodium. Small amounts of potassium calcium and phsophate are also present.

Stimulation of pancreatic secretions: the entry of partially digested semisolid food (chime) form stomach into duodenum stimulates secretion of secreting by the duodenum. Secreting is a hormone and is carried by blood to the pancreases where it stimulates its secretion. The secreting itself is said to exist as prose cretin in the duodenal mucosa. The acid (HCl) present in chime converts this to secreting. It is a small polypeptide containing 27 amino acids and has a low molecular with (5,000). Another produces as bicarbonate rich pancreatic jive pancreozymin induces an enzyme rich secretion stimulation of vague also induces an enzyme rich secretion. Pancreatic juice can be collected and studied by introducing a duodenal tube removing the resting contents and then injecting secreting to stimulate pancreatic secretion.

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